Curriculum Vitae

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I. NICK VIAL MD
Curriculum Vitae

CONTACT INFORMATION

invMD Plastic Surgery
(541) 317-0808
2450 NE Mary Rose Pl
Ste 201
Bend, OR 97701

EMPLOYMENT

invMD Plastic Surgery
Private Practice
2017-Present
Resident Physician
Department of Plastic Surgery
University of Pittsburgh
2011-2017

EDUCATION

Stanford University School of Medicine
Stanford, California
MD Degree
2004-2011
New York University
New York, New York
BA Degree
2000-2004

SELECTED HONORS/AWARDS

Peter J. Gingrass, MD Award (Plastic Surgery Research Council 2009)
Hagey Family Research Fellowship (Stanford University 2008-2009)
Excellence in Adipose Stem Cell Research (International Federation for Adipose Therapeutics & Science 2007)
Stanford Medical Scholars Research Fellowship (Stanford University 2006-2007)
Phi Beta Kappa (New York University 2004)
Founders’ Day Award (New York University 2004)
New York University College of Arts & Sciences Merit Scholarship (New York University 2002-2004)
Dr. Charles Barbieri Research Scholar (New York University 2002)
Dean’s Circle University Scholar (New York University 2001-2002)
University Athletic Association Student-Athlete Academic Honor Roll (New York University 2000-2004)
Dean’s List (New York University 2000-2004)

RESEARCH EXPERIENCE

Stanford University School of Medicine, Hagey Laboratory
Research Fellow
Advisor: Geoffrey C. Gurtner, MD
2006-2011
New York University, Department of Biology
Undergraduate Researcher
Advisor: Ignatius P. Tan, PhD.
2000-2004

COLLEGIATE ATHLETICS

Men’s Fencing Team, New York University
Varsity Starter on UAA Championship Team
Nationally Ranked (2000)
2000-2004

PATENT

Profiling of Cell Populations
United States Patent Number 8,586,305

PUBLICATIONS

1 Vial IN, Rubin JP. Commentary on: Isolation and Differentiation Potential of Human Mesenchymal Stem Cells
from Adipose Tissue Harvested by Water Jet-Assisted Liposuction.
Aesthetic Surgery Journal, Nov. 2015
2 Januszyk M, Sorkin M, Glotzbach JP, Vial IN, Maan Z, Rennert RC, Duscher D, Thangarajah H, Longaker MT, Butte AJ, Gurtner GC. Diabetes Irreversibly Depletes Bone Marrow-Derived Mesenchymal Progenitor Cell Subpopulations.
Diabetes, Apr. 2014
3 Januszyk M, Wong VW, Bhatt KA, Vial IN, Paterno J, Longaker MT, Gurtner GC. Mechanical offloading of incisional wounds is associated with transcriptional downregulation of inflammatory pathways in a large animal model.
Organogenesis, Apr. 2014
4 Wong VW, Rustad KC, Akaishi S, Sorkin M, Glotzbach JP, Januszyk M, Nelson ER, Levi K, Paterno J, Vial IN, Kuang AA, Longaker MT, Gurtner GC. Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling.
Nature Medicine, Dec. 2011
5 Gurtner GC, Dauskardt RH, Wong VW, Bhatt KA, Wu K, Vial IN, Padois K, Korman JM, Longaker MT. Improving cutaneous scar formation by controlling the mechanical environment: large animal and phase I studies.
Annals of Surgery, Aug. 2011
6 Vial IN*, Glotzbach JP*, Januszyk M*, Wong VW, Gelbard A, Kalisky T, Thangarajah H, Longaker MT, Quake SR, Chu G, Gurtner GC. An information theoretic, microfluidic-based single cell analysis permits identification of subpopulations among putatively homogeneous stem cells.
PLoS One, Jun. 2011

*Equally Credited Authors
7 Vial IN*, Paterno J*, Wong VW, Rustad KC, Sorkin M, Shi Y, Bhatt KA, Thangarajah H, Glotzbach JP, Gurtner GC. Akt-Mediated Mechanotransduction in Murine Fibroblasts during Hypertrophic Scar Formation.
Wound Repair and Regeneration, Feb. 2011

*Equally Credited Authors
8 Thangarajah H, Vial IN, Grogan RH, Yao D, Shi Y, Januszyk M, Galiano RD, Chang EI, Galvez MG, Glotzbach JP, Wong VW, Brownlee M, Gurtner GC. HIF-1α Dysfunction in Diabetes.
Cell Cycle, Jan. 2010
9 Thangarajah H, Yao D, Chang EI, Shi Y, Jazayeri L, Vial IN, Galiano RD, Du XL, Grogan R, Galvez MG, Januszyk M, Brownlee M, Gurtner GC. The Molecular Basis for Impaired Hypoxia-Induced VEGF Expression in Diabetic Tissues.
Proceedings of the National Academy of Sciences, Aug. 2009
10 Hamou C*, Callaghan MJ*, Thangarajah H, Chang E, Chang EI, Grogan RH, Paterno J, Vial IN, Jazayeri L, Gurtner GC. Mesenchymal Stem Cells Can Participate in Ischemic Neovascularization.
Plastic and Reconstructive Surgery, Feb. 2009
11 Vial IN*, Thangarajah H*, Chang E, El-Ftesi S, Januszyk M, Chang EI, Paterno J, Neofytou E, Longaker MT, Gurtner GC. IFATS Series: Adipose Stromal Cells Adopt a Proangiogenic Phenotype Under the Influence of Hypoxia.
Stem Cells, Oct. 2009

*Equally Credited Authors
12 Loh S, Chang EI, Galvez MG, Thangarajah H, Hamou CD, Vial IN, El-ftesi S, Lin D, Gurtner GC. SDF-1α Expression During Wound Healing in the Aged is HIF Dependent.
Plastic and Reconstructive Surgery, Feb. 2009
13 Chang EI, Bonillas RG, El-Ftesi S, Chang EI, Ceradini DJ, Vial IN, Chan DA, Michaels J 5th, Gurtner GC. Tissue Engineering using Autologous Microcirculatory Beds as Vascularized Bioscaffolds.
Federation of American Societies for Experimental Biology, Nov. 2008

ABSTRACTS

1 James I, Vial IN, De La Cruz C. Vacuum Infiltration as a Means of Small Molecule Delivery into Acellular Dermal Matrix.
Robert H. Ivy Society, 2015
2 Maan ZN, Ho N, Rennert RC, Duscher D, Sorkin M, Rodrigues M, Chen JS, Vial IN, Perez M, Findlay M, Gurtner GC. Endothelial Cell Production of SDF-1 Critically Regulates Cytokine Expression and Neovascularization during Wound Healing.
American College of Surgeons, 2014
3 James I, Vial IN, Acarturk TO. Free flap reconstruction of the hypopharynx: An analysis of patients and outcomes at the University of Pittsburgh from 2002 to 2012.
Robert H. Ivy Society, 2014
4 Zammerilla LL, Vial IN, Chavanon VA, Sirvastava U, Zhang X, Russavage JM, Manders EK, Acarturk TO. Paraspinous Muscle Flaps for Closure of Midline Post-Spinal Surgery Defects.
Robert H. Ivy Society, 2013
5 Vial IN, Glotzbach JP, Januszyk M, Thangarajah H, Wong VW, Longaker MT, Gurtner GC. Single Cell Analysis as a Model to Better Isolate Stem Cell Populations.
Plastic Surgery Research Council, 2010.
†Presenter
6 Vial IN†, Glotzbach JP, Januszyk M, Thangarajah H, Chang E, Longaker MT, Gurtner GC. Diabetic Mesenchymal Stem Cells Lack a Population of Cells that Express Genes Needed to Maintain Pluripotentcy as Determined by Microfluidic Single Cell Transcriptional Analysis.
Plastic Surgery Research Council, 2009.
American Association of Plastic Surgeons, 2010 (by invitation)

†Presenter
7 Bhatt KA, Vial IN, WU K, Wong VW, Dauskardt RH, Longaker MT, Gurtner GC. Mechanical Stresses Determine Scarring During Wound Healing.
Plastic Surgery Research Council, 2010.
8 Glotzbach JP, Vial IN, Januszyk M, Wong VW, Thangarajah H, Longaker MT, Gurtner GC. Single Cell Analysis Demonstrates Significant Transcriptional Heterogeneity within Tightly-Sorted Murine Hematopoietic Stem Cell Populations.
Academic Surgical Congress, 2010.
9 Wong VW, Bhatt KA, Vial IN, Wu K, Padois K, Dauskardt RH, Longaker MT, Gurtner GC. Beyond Langer’s Lines: Manipulating Wound Mechanical Forces to Control Hypertrophic Scar Formation in the Red Duroc Pig
American College of Surgeons, Surgical Forum, 2010.
10 Glotzbach JP, Januszyk M, Vial IN, Wong VW, Thangarajah H, Galvez MG, Longaker MT, Gurtner GC. Defects in Mesenchymal Stem Cells are Evident with Single Cell Transcriptional Analysis.
Wound Healing Society, 2010
11 Wong VW, Rustad KC, Vial IN, Glotzbach JP, Januszyk M, Major MR, Paterno J, Longaker MT, Gurtner GC. Focal Adhesion Kinase is Critical in Maintaining Mechanical Homeostasis during Hypertrophic Scar Formation.
Wound Healing Society, 2010.
12 Glotzbach JP, Levi B, Januszyk M, Vial IN, Wong VW, Rustard KC, Longaker MT, Gurtner GC. Single Cell Transcriptional Analysis Defines Multiple Heterogeneous Subpopulations Within Human Adipose Derived Stromal Cells.
Plastic Surgery Research Council, 2010.
13 Glotzbach JP, Levi B, Wong VW, Januszyk M, Vial IN, James AW, Sorkin M, Longaker MT, Gurtner GC. Defining Functionally Distinct Subpopulations of Human Adipose-Derived Stromal Cells Through Single Cell Transcriptional Analysis.
American College of Surgeons, Surgical Forum, 2010
14 Wong VW, Glotzbach JP, Rustad KC, Major MR, Vial IN, Gurtner GC. In-Vitro and In-Vivo Mechanotransduction of Focal Adhesion Kinase-Mediated MCP-1 Signaling During Hypertrophic Scar Formation.
Academic Surgical Congress, 2010.
15 Major M, Galvez MG, Chang EI, Wong VW, Glotzbach JP, Vial IN, Gurtner GC. Reactive Oxygen Species Accumulation Leads to Deficient Wound Healing Similar to Aging.
Plastic Surgery Research Council, 2010.
16 Wong VW, Glotzbach JP, Paterno J, Rustad KC, Sorkin M, Major MR, Vial IN, Longaker MT, Gurtner GC. Mechanical Modulation of Inflammation and Skin Fibrosis Through CD4+ T Cell Signaling.
American College of Surgeons, Surgical Forum, 2010
17 Vial IN, Wong VW, Paterno J, Galvez MG, Gurtner GC. Evaluating the Effect of Mechanical Strain on Hypertrophic Scar Formation in Focal Adhesion Kinase Knockout Mice.
Plastic Surgery Research Council, 2009.
18 Glotzbach JP, Vial IN, Januszyk M, Thangarajah H, Wong VW, Galvez MG, Ko SH, Longaker MT, Gurtner GC. A Novel Single Cell Gene Expression Analysis Identifies Critical Gene Transcription Defects in Diabetic Murine Mesenchymal Stem Cells.
American College of Surgeons, Surgical Forum, 2009
19 Januszyk M, Vial IN, Glotzbach JP, Thangarajah H, Gurtner GC. Applying Fuzzy Logic to Detect Novel Subpopulations of Mesenchymal Stem Cells.
Plastic Surgery Research Council, 2009
20 Januszyk M, Vial IN, Glotzbach JP, Thangarajah H, Wong VW, Galvez MG, Longaker MT, Gurtner GC. A Novel Approach to Evaluate Heterogeneity in Stem Cell Populations using Fuzzy Logic and Microfluidic Single Cell Technology.
American College of Surgeons, Surgical Forum, 2009.
21 Januszyk M, Vial IN, Glotzbach JP, Thangarajah H, Galvez MG, Wong VW, Longaker MT, Gurtner GC. Computational Analysis of Stem Cell Population Heterogeneity and its Implications for Diabetic
Neovascularization using Microfluidic Single Cell Technology.
American Society for Clinical Investigation 2009.
22 Wong WV, Vial IN, Paterno JM, Galvez MG, Glotzbach JP, Januszyk M, Longaker MT, Gurtner GC. Altered Mechanotransduction Profiles in Skin Layer-Specific Focal Adhesion Kinase (FAK) Knockout Mice.
American College of Surgeons, Surgical Forum, 2009.
23 Glotzbach JP, Thangarajah H, Vial IN, Chang E, Januszyk M, Gurtner GC. Hematopoietic Stem Cells Prevent Angiogenic Differentiation of Mesenchymal Stem Cells.
Plastic Surgery Research Council, 2009.
24 Galvez MG, Chang EI, Glotzbach J, Major M, Vial IN, Thangarajah H, Rajadas J, Gurtner GC. Pullulan Delivery Film for Targeted Ischemic Preconditioning.
Plastic Surgery Research Council, 2009.
25 Vial IN†, Thangarajah H, Bhatt KA, Paterno J, Gurtner GC. Evaluating the Regenerative Capacity of Cultured and Primary Bone Marrow Derived Cells using Real-Time Bioluminescent In-Vivo Imaging.
Plastic Surgery Research Council, 2008.
†Presenter
26 Bhatt KA, Vial IN, WU K, Kelantan MS, Binyamin G, Park Y, Dauskardt RH, Longaker MT, Gurtner GC. Anatomical Variations of Mechanical Stress on Swine Wounds — Correlation with Human Hypertrophic Scars.
American College of Surgeons, Surgical Forum, 2008.
27 Gupta DM, Vial IN, Lee JK, Wan DC, Gurtner GC, Longaker MT. TAZ is a transcriptional modulator of human adipose-derived stromal cell differentiation towards the osteogenic lineage.
Plastic Surgery Research Council, 2008.
28 Thangarajah H, Vial IN†, Chang E, El-Ftesi, Chang EI, Bhatt KA, Paterno JM, Gurtner GC. Hypoxic Regulation of Proangiogenic Adipose-Derived Mesenchymal Stem Cell Function.
American College of Surgeons, Surgical Forum, 2008.
†Presenter.
29 Bhatt KA, Rajadas J, Thangarajah H, Vial IN, Olorunnipa S, Longaker MT, Gurtner GC. Replicating Fetal Matrix Ligand Domains to Promote Tissue Regeneration.
American College of Surgeons, Surgical Forum, 2008.
30 Paterno J, Bhatt KA, Kelantan M, Vial IN, Chang E, Thangarajah H, Gurtner GC. In-Vivo Temporal And Mechanical Load Dependent Analysis of Microarray Expression Profiles in Hypertrophic Scar Formation Demonstrates Unique Fibrotic and Inflammatory Signatures.
Plastic Surgery Research Council, 2008.
31 Thangarajah H, Yubin S, Yao D, Jazayeri L, Chang EI, Vial IN, Galiano RD, Ceradini DJ, Brownlee M, Gurtner GC. Diabetes Impairs the Hypoxia Response by Blocking Hypoxia Inducible Factor-1a binding to P300.
American College of Surgeons, Surgical Forum, 2008.
32 Thangarajah H, Vial IN†, Chang E, Chang EI, Paterno JM, Gurtner GC. Adipose-Derived Mesenchymal Stem Cells Mobilize to Sites of Ischemia and Participate in Postnatal Neovascularization.
International Federation of Adipose Therapeutics and Science 2007.

†Presenter
33 Thangarajah H, Chang E, Vial IN, Gurtner GC. Mobilization of Bone Marrow Resident Mesenchymal Stem Cells is Impaired in Diabetes.
American College of Surgeons, Surgical Forum, 2007.
34 Loh SH, Chang EI, Vial IN, Galvez MG, Lin D, Gurtner GC. Aging Impairs IL 1-b Induced SDF-1 Expression through Decreased HIF-1a Stabilization.
Plastic Surgery Research Council, 2007.
35 Kelantan MS, Slater B, Chang E, Paterno JM, Vial IN, Longaker MT, Gurtner GC. Role of T Lymphocytes in the Formation of Hypertrophic Scars.
Plastic Surgery Research Council, 2007.
36 Vial IN†, Ghiassi-Nejad Z, Sukarna T, Nadel J, Ajmera P, Bavichi S, Arriaza J, Tan IP. Suppression of Cx43 Expression via RNA Interference.
American Society for Cell Biology, 2003.
†Presenter.